by Nature Medicine
Findings from a Phase II study suggest that ciltacabtagene autoleucel (cilta-cel), which is thought to be more effective when delivered in earlier disease states, has promise in the setting of...
by Transplantation and Cellular Therapy
Post-transplantation cyclophosphamide (PTCy) is gaining traction as standard prevention against graft-versus-host disease (GVHD) following allogeneic hematopoietic cell transplantation (HCT), but...
by Frontiers in Immunology
Irradiating tumors before administering chimeric antigen receptor (CAR) T-cell therapy may boost CAR T-cell infiltration and improve efficacy in solid tumors, researchers report.
by Cancer Discovery
Scientists have developed a construct that they say overcomes challenges specific to using chimeric antigen receptor (CAR)-T cells to treat individuals with acute myeloid leukemia (AML).
by Bone Marrow Transplantation
Researchers describe a novel reduced-intensity conditioning protocol that could potentially resolve a common treatment barrier for adults with sickle cell disease (SCD). Children with SCD...
by Blood Advances
The best timeline for SARS-CoV-2 immunization after undergoing cellular therapy is not known, but recent findings indicate that mRNA SARS-CoV-2 vaccination within 4 months does not appear to...