by Clinical Cancer Research
The efficacy of chimeric antigen receptor (CAR) T-cell therapy targeting interleukin 13 receptor α2 (IL13Rα2) for patients with malignant gliomas has yet to be determined, but Phase I evidence...
by Transplantation and Cellular Therapy
A retrospective analysis suggests that cellular immunotherapy may offer a survival advantage over pharmacological immunosuppression in the setting of graft-versus-host disease (GVHD) following...
by Blood
Researchers suspect immunosenescence may be implicated when chimeric antigen receptor (CAR) T-cell therapy fails in the setting of chronic lymphocytic leukemia (CLL).
by ACS Applied Materials & Interfaces
Researchers describe a new process that overcomes the limitations of established practices for manufacturing natural killer (NK) cells that express chimeric antigen receptors (CAR).
by Nature Medicine
Additional study of mivocabtagene-autoleucel (miv-cel) is warranted for the treatment of rheumatoid arthritis (RA) based on evidence demonstrating acceptable tolerability in the short term,...
by Transplantation and Cellular Therapy
Researchers behind a first-in-human clinical study say their work supports the use of adoptive regulatory T cells (Treg) to combat graft-versus-host disease (GVHD) following allogeneic...