Trending topics and news in HCT and Cellular Therapy

Chimeric antigen receptor (CAR) T-cell treatment has had limited success against pancreatic ductal adenocarcinoma (PDAC), but there is hope that incorporating ibrutinib or PD-1 blockade might...

Scientists developed a conditioning protocol that, followed by allogeneic bone marrow transplantation and islet transplantation, produces a favorable mix of host and donor hematopoietic stem cells...

The results of a prospective study favor the use of a standardized protocol for allogeneic hematopoietic stem cell transplantation (HSCT) in pediatric patients with a particular type of B-cell...

Donor traits and graft sources have a role in how outcomes play out after haploidentical hematopoietic cell transplantation (HCT) for acute lymphoblastic leukemia (ALL), report members of a...

Preclinical evidence warrants further testing of P2X7 blockades as a preventative therapy against graft-versus-host disease (GVHD), a complication of allogeneic hematopoietic stem cell...

IFNγ blockade curtails the incidence of high-grade toxicities associated with chimeric antigen receptor (CAR) T-cell therapy, researchers report. Observations from a murine model of toxicities...