by Molecular Therapy
Scientists have developed a model to assess the efficacy of mRNA-based chimeric antigen receptor (CAR) T cells, which are understudied despite their potential in treating glioblastoma (GBM) and...
by Blood
Innate lymphoid cells (ILCs) derived from hematopoietic stem cells mitigate graft-versus-host disease (GVHD) in human and mice models but, until now, how they do so has not been fully understood.
by Blood Advances
A real-world study affirmed the safety and efficacy of belumosudil in patients with chronic graft-versus-host disease (cGVHD) while also comparing its performance relative to best available...
by Transplantation and Cellular Therapy - The Official Journal of ASTCT
Retrospective data suggest concerns typically associated with HLA-DQB1-mismatched donors in hematopoietic cell transplantation (HCT) may not be relevant in the context of post-transplantation...
by Cancer Immunology Research
Researchers believe endoglin (ENG), with its capacity to deliver comprehensive tumor targeting, could advance the use of chimeric antigen receptor (CAR) T-cell therapy to treat advanced sarcomas....
by Blood Advances
Researchers hope their novel but simple approach to rapid expansion of homogenous human type II innate lymphoid cells (ILC2) provides another option for preventing or treating graft-versus-host...