by Biomedicine & Pharmacotherapy
Scientists say that aiming chimeric antigen receptor (CAR) T cells at both B7-H3 and B cell maturation antigen (BCMA), which is effective alone but still vulnerable to therapeutic resistance,...
by Blood
Observations from a mouse model of graft-versus-host disease (GVHD) shed light on the role Enterococcus faecalis plays in this complication of allogeneic hematopoietic cell transplantation...
by Nature Medicine
Researchers are encouraged by the early performance of multi-antigen T-cells in the setting of pancreatic ductal adenocarcinoma (PDAC), a cancer that has largely resisted immunotherapy.
by Transplantation and Cellular Therapy
Researchers agree on the robust potential of belumosudil as a treatment for chronic graft-versus-host disease (cGVHD), which can develop following allogeneic hematopoietic stem cell...
by Clinical Cancer Research
Chimeric antigen receptor (CAR) T-cell treatment has had limited success against pancreatic ductal adenocarcinoma (PDAC), but there is hope that incorporating ibrutinib or PD-1 blockade might...
by Journal of Clinical Investigation
Scientists developed a conditioning protocol that, followed by allogeneic bone marrow transplantation and islet transplantation, produces a favorable mix of host and donor hematopoietic stem cells...