by Journal for ImmunoTherapy of Cancer
Chimeric antigen receptor (CAR) T-cell therapy has not achieved the same level of success with solid tumors as it has with hematological cancers, but results of a preclinical experiment suggest...
by Diabetes Technology & Therapuetics
Designing chimeric antigen receptor (CAR) T regulatory cells (Tregs) to detect glutamic acid decarboxylase, 65 kD isoform (GAD65) has the potential to reverse type 1 diabetes (T1D) in adults,...
by Blood
Phase III study results support Orca-T immunotherapy as a novel intervention and less toxic alternative to traditional tacrolimus and methotrexate (Tac/MTX) for GVHD prophylaxis following...
by Bone Marrow Transplantation
Results of a systematic review and meta-analysis affirm eltrombopag as a viable intervention against thrombocytopenia, a complication of allogeneic hematopoietic cell transplantation (allo-HCT).
by Clinical Cancer Research
After developing a chimeric antigen receptor (CAR) construct to address features of pancreatic ductal adenocarcinoma (PDAC) that resist CAR T-cell treatment, researchers explored actionable...
by Blood Advances
FMS-like tyrosine kinase 3 (FLT3) is considered a viable and selective target for immunotherapy against acute myeloid leukemia (AML), based on new research.