by Science Translational Medicine
Investigators designed chimeric antigen receptor (CAR) T cells to work against vascular endothelial growth factor A (VEGF), a protein that contributes to immunosuppressive tumor microenvironments...
by Blood
Scientists have identified CSF-1R blockade combined with lenalidomide maintenance therapy as a promising pathway to better progression-free survival following autologous stem cell transplantation...
by Blood Advances
New research findings provide additional insight into the complexities of care in older patients who have undergone blood or marrow transplants. There is limited knowledge on the subject, but...
by Bone Marrow Transplantation
Although little is known about deletion of the long arm of chromosome 20 [del(20q)], a donor-derived cytogenetic abnormality that can occur after allogeneic hematopoietic cell transplantation...
by Neuro-Oncology
Chimeric antigen receptor (CAR) T cells targeting B7-H3 show promise in treating diffuse intrinsic pontine glioma (DIPG), but researchers suspect the true potential of this approach will only be...
by Transplantation and Cellular Therapy
While an immunosuppressive tumor microenvironment (TME) limits the efficacy of chimeric antigen receptor (CAR) immunotherapy in solid tumors, lab experiments suggest the treatment could advance by...