by Cancer Immunology Research
Researchers developed CD176-targeted CAR T cells and found that IL-12–enhanced constructs demonstrated the strongest antitumor activity in preclinical models of non-small cell lung cancer....
by Transplantation and Cellular Therapy
Researchers found that aging significantly affects hematopoietic stem cell function, immune recovery, and blood cell development after bone marrow transplantation. The findings highlight how donor...
by Transplantation and Cellular Therapy
A retrospective study found that patients with lymphoma and HIV who underwent hematopoietic cell transplantation experienced similar rates of complications, hospitalization, and survival as...
by Blood Advances
A phase II study found that topical clobetasol 0.05% solution produced a 91% overall response rate in patients with oral chronic graft-versus-host disease (cGVHD), significantly improving oral...
by Clinical Cancer Research
The efficacy of chimeric antigen receptor (CAR) T-cell therapy targeting interleukin 13 receptor α2 (IL13Rα2) for patients with malignant gliomas has yet to be determined, but Phase I evidence...
by Transplantation and Cellular Therapy
A retrospective analysis suggests that cellular immunotherapy may offer a survival advantage over pharmacological immunosuppression in the setting of graft-versus-host disease (GVHD) following...