by Clinical Cancer Research
Early research suggests leucine rich repeat containing 15 (LRRC15), which is highly present in osteosarcoma tumors but limited in normal tissues, has potential as a target antigen for chimeric...
by Blood
Experiments with mice and observations in humans justify clinical trial evaluation of pentagastrin as an intervention against acute graft-versus-host disease (aGVHD), researchers report.
by Transplantation and Cellular Therapy
Investigators believe cytokine-induced killer (CIK) cell infusion, administered after autologous stem cell transplantation (ASCT), may represent a viable postremission regimen for patients with...
by Blood
Research findings showcase betibeglogene autotemcel (beti-cel) as a viable and potentially curative intervention for transfusion-dependent ß-thalassemia (TDT). In this setting, hematopoietic stem...
by Journal for ImmunoTherapy of Cancer
Chimeric antigen receptor (CAR) T-cell therapy has not achieved the same level of success with solid tumors as it has with hematological cancers, but results of a preclinical experiment suggest...
by Diabetes Technology & Therapuetics
Designing chimeric antigen receptor (CAR) T regulatory cells (Tregs) to detect glutamic acid decarboxylase, 65 kD isoform (GAD65) has the potential to reverse type 1 diabetes (T1D) in adults,...