Joint ASTCT-EBMT Basic and Translational Scientific Meeting

The Joint ASTCT and EBMT Basic and Translational Scientific Meeting will be a 2.5-day conference focused on cutting-edge basic and translational biology in the field. The meeting will focus on fundamental themes and novel technologies with an emphasis on unpublished and innovative science. Attendance to the meeting will be limited to 120 attendees with afternoon breaks to allow for informal networking opportunities between junior and senior attendees. The meeting will host two days of poster sessions and a best oral abstract session.

DETAILS:

Tuesday, May 23 - Friday, May 25, 2023
Eurostars Sitges
Av. Camí de Miralpeix, 12, 08870 Sitges, Barcelona
Sitges, Barcelona (Spain)

ABSTRACT SUBMISSION

ASTCT and EBMT are soliciting abstracts that highlight the best of basic and translational science. Abstracts will be evaluated on their importance and relevance to the field, as well as originality and innovation in problem solving. Selected data and/or research will be showcased at the poster area. Moreover, top scoring abstracts will be selected as Oral Presentations and integrated in the program.

Submit Your Abstract

IMPORTANT DEADLINES

Opening Submission: December 21, 2022
Submission Deadline: March 18, 2023
Notification: TBD

TOPICS

Immune metabolism
GVHD
Stem cell biology
Cell engineering
Anti-leukemic strategies

HOUSING

ASTCT and EBMT have reserved rooms at a discounted rate at Eurostars Sitges Hotel. Information on how to make a hotel reservation will be distributed in the registration confirmation email.

Room Rate: 186.80€ Double room for Single Use/Night. Breakfast, VAT and local taxes included

TARGET AUDIENCE

The program is intended for both junior and senior members of the blood and marrow transplantation and cellular therapy field.

This conference is only for physicians and scientists who are currently practicing in the field of transplantation and cellular therapy and sponsoring companies. Please contact Yaiza Gonzalez if you are interested in participating as a sponsor.

REGISTRATION

Registration to this event is limited to a maximum of 120 total attendees. We are unable to accept additional registrants once the registration capacity has been met.

REGISTER

Type	Price
Junior Attendee Rate*	125€
Senior Attendee Rate	250€

*Junior attendees are defined as post doctoral fellows, current fellows, and junior faculty within the first three years of appointment.

PROGRAM AGENDA

Tuesday, May 23

Time	Session
9:00 - 9:15 AM	Welcome and Introduction
Immune Metabolism Session Chair: Bruce Blazar, MD; University of Minnesota, US
9:15 - 9:45 AM	Metabolic control of T cell differentiation in cancer Greg Delgoffe, PhD; University of Pittsburgh, US
9:45 - 10:15 AM	Metabolic reprogramming of T cells to enhance GVL effects Prof. Dr. Robert Zeiser; University of Freiburg, DE
10:15 - 10:45 AM	Obesity, inflammation and cancer Jeffrey Rathmell, PhD; Vanderbilt University Medical Center, US
10:45 - 10:55 AM	Oral Abstract Presentation
10:55 - 11:05 AM	Oral Abstract Presentation
11:05 - 11:15 AM	Oral Abstract Presentation
11:15 - 11:30 AM	Break
Graft vs Host Disease Session Chair: Warren Schlomchik, MD; University of Pittsburgh, US
11:45 - 12:15 PM	Target tissue: Tolerance and reminiscence Pavan Reddy, MD; Baylor College of Medicine, US
12:15 - 12:45 PM	T-cell Exhaustion and GVHD/GVL Takanori Teshima, MD; Hokkaido University Hospital, JP
12:45 - 1:15 PM	Anti-C19 CAR CD8 induced Tregs cell therapy to optimize GVHD/GVL outcome Bruce Blazar, MD; University of Minnesota, US
1:15 - 1:25 PM	Oral Abstract Presentation
1:25 - 1:35 PM	Oral Abstract Presentation
1:35 - 1:45 PM	Oral Abstract Presentation
1:45 - 5:30 PM	Lunch + Afternoon Break
5:30 - 6:30 PM	Poster Tour + Networking Hour
6:30 - 8:30 PM	Keynote Lecture and Dinner Megan Skyes, MD; Columbia University Medical Center, US

Wednesday, May 24

Time	Session
Stem Cell Biology Session: Markus Manz, MD; University Hospital Zurich, CH
9:00 - 9:35 AM	Harnessing the microenvironmental regulation for improved outcomes of HSCT Markus Manz, MD; University Hospital Zurich, CH
9:35 - 10:10 AM	The microbiome-IL-1 axis drives HSC inflamm-aging and clonal hematopoiesis Simón Méndez-Ferrer, PhD; University of Cambridge, UK
10:10 - 10:45 AM	Non-genotoxic anti-CD117 antibody conditioning in hematopoietic stem cell transplantation Judith Shizuru, MD; Stanford University, US
10:45 - 11:00 AM	Oral Abstract Presentation
11:00 - 11:30 AM	Break
Cell Engineering Session Chair: Chiara Bonini, MD; I.R.C.C.S Ospedale San Raffaele, IT
11:30 - 12:05 PM	CAR T cells for brain tumors Crystal Mackall, MD; Stanford University, US
12:05 - 12:40 PM	The UCL CAR T programme: Better Targets, Better Targeting Claire Roddie, MD; University College London, UK
12:40 - 1:15 PM	Modulating T cell memory and tumor glycosylation to improve CAR T cell therapy Monica Casucci, PhD; I.R.C.C.S Ospedale San Raffaele, IT
1:15 - 1:30 PM	Oral Abstract Presentation
1:30 - 5:30 PM	Lunch + Afternoon Break
5:30 - 6:30 PM	Meet-the-Profession Session
6:30 - 8:30 PM	Keynote Lecture and Dinner Luigi Naldini, MD, PhD; I.R.C.C.S Ospedale San Raffaele, IT

Friday, May 25

Time	Session
Anti-Leukemic Strategies and NK Cells (Part I) Session Chair: Nicolaus Kröger, MD; University Hospital Hamburg-Eppendorf, DE
9:00 - 9:30 AM	Factors determining the transition from clonal hematopoiesis to myeloproliferative neoplasms and progression to myelofibrosis Speaker: Prof. Dr. Radek Skoda; University Hospital Basel, CH
9:30 - 10:00 AM	Off-The-Shelf targeted NK cell therapies to treat leukemia Jeffrey Miller, MD; University of Minnesota, US
10:00 - 10:30 AM	Effect of pre-leukemic mutations on hematopoietic stem cell and their progenies Dominique Bonnet, PhD; Francis Crick Institute, UK
10:30 - 11:00 AM	TCR-T cell therapy for leukemia post-transplantation Marie Bleakley, MD, PhD; Fred Hutchinson Cancer Center, US
11:00 - 11:30 AM	Break
Anti-Leukemic Strategies and NK Cells (Part II) Session Chair: Harry Dolstra, PhD; Radboud University Medical Centre, NL
11:30 - 12:00 PM	Training NK cells for enhanced leukemia attack Todd Fehniger, MD, PhD; Washington University School of Medicine, US
12:00 - 12:30 PM	Editing of T and HASC for improved CART function John DiPersio, MD, PhD; Washington University School of Medicine, US
12:30 - 12:40 PM	Oral Abstract Presentation
12:40 - 12:45 PM	Closing Remarks