Titans of Transplant Featuring Dr. Crystal Mackall

In this episode of ASTCT Talks, Dr. Nirali Shah welcomes Crystal Mackall, MD, the Ernest and Amelia Gallo Family Professor at Stanford University and a pioneer in immuno-oncology and cellular therapy, for a conversation in the Titans of Transplant series.

Dr. Mackall reflects on her journey into medicine, the mentors who shaped her career, and the evolution of immunotherapy from an emerging concept to a transformative treatment modality. She also shares her perspective on the future of cell and gene therapies, the challenges facing pediatric cancer drug development, and the importance of resilience, mentorship, and innovation in scientific careers.

Tune in to hear about:

• Dr. Mackall's path to becoming a physician-scientist
• Lessons learned from mentors and decades of leadership in the field
• The evolution of immunotherapy and cellular therapy
• Emerging opportunities in RNA-based therapeutics and next-generation treatments
• Barriers to advancing pediatric cancer therapies
• Advice for trainees and early-career investigators
• The role of resilience, collaboration, and curiosity in a successful career

Listen to the episode below or on your favorite podcast app. Subscribe to ASTCT Talks to stay up to date on the latest conversations in transplantation and cellular therapy.